Aggressive Fluid and Sodium Restriction in Acute Decompensated Heart Failure
The objective of this
study was to determine if the effects of an aggressive fluid-restricted and
sodium-restricted diet differed from the effects with no such restrictions on
weight loss and clinical stability throughout a three day period in
hospitalized patients with acute decompensated heart failure (ADHF). Sodium and
fluid restrictions are therapeutic remedies that have been used to treat ADHF
universally. However, there is a lack of evidence based research to conclude
that there is improvement to reach clinical stability in patients with ADHF.
A total of 813 patients
admitted with ADHF were assessed for eligibility. The study included 75 adults
diagnosed with systolic dysfunction, ADHF, and a thirty-six hour inpatient
length of stay or less. The control group (n=37) was prescribed the standard
hospital diet which included a liberal sodium and fluid intake diet while the
intervention group (n=38) followed a maximum fluid intake of 800 mL per day and
maximum sodium restriction of 800 mg per day. The primary measured outcomes included
weight loss and clinical stability at the three day assessment.
Weight loss was similar
in both groups as well as clinical congestion score at day three. The
intervention group reported increased levels of thirst and readmission rate at
thirty days showed no difference between groups. Patients in the intervention
group had more congestion than their constituents in the control group at the
thirty day follow-up. Average BNP levels were elevated and similar in both
groups. At the end of the study, both groups had a similar reduction in mean BNP
levels.
In conclusion,
aggressive sodium restriction coupled with fluid restriction in patients with
ADHF did not show improved outcomes in weight loss or clinical stability at day
three because no effect had been proven. The study suggests that it may be safe
to recommend liberalizing fluid and sodium restrictions in patients with ADHF. This
poses new implications for clinical dietitian application. Due to the
relatively small differences in interventions, doubts still remain as to the
potential harm or benefit of fluid and sodium restrictions.
Aliti GB, Rabelo ER,
Clausell N, Rohde LE, Biolo A, Beck-da-Silva L. Aggressive fluid and sodium restriction
in acute decompensated heart failure: a randomized clinical trial. JAMA Intern Med. 2013;173(12):1058-1064.
doi:10.1001/jamainternmed.2013.552.
SK
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